Shandong Binzhou Zhiyuan Biotechnology CO., ltd
Shandong Binzhou Zhiyuan Biotechnology CO., ltd have 4 series (Medical Cyclodextrins, Cyclodextrin Reagents, Cyclodextrin Complexes, Cyclodextrin Polymers ) of more than 40 kinds of cyclodextrins now.
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DMF No.: 030168
Name: hydroxypropyl- beta-cyclodextrin
Other name : hydroxypropyl betadex ; 2-hydroxypropyl-beta-cyclodextirn ;
Hydroxypropyl-β-cyclodextrin .
Abbreviation : HPBCD
CAS: 128446-35-5; 94035-02-6; 136019-12-0
EINECS: 420-920-1
Molecular formula :C42H70-nO35(C3H8O2)n
Molecular weight: 1134.98+58n
Solubility(in 100cm3 solvent, at 25℃) : water: >180 g
Methanol: >33g
DMSO: >33g
Qaulity : Pharma grade / food grade / cosmetics grade / industry grade
Standard : USP38/ EP8.0 / CP2015
Package: 500g/bag , 2kg/bag, 10kg/drum , 20kg/drum or customized
Use : medical food chemical cosmetic other industries
Specification :
| ITEMS | SPECIFICATION(USP38) | RESULTS |
| Appearance | white powder, insipid, innocent | Qualify |
| Assay | ≥98％ | 99.5% |
| Degree of Substitution | 2.8-10.5 | 5.5 |
| Clarity of solution | 50%(w/v) water solution is clear | clear |
| Identification(IR) | same absorption bands with USP Hydroxypropyl Betadex RS | Qualify |
| Loss on Drying | ≤10％ | 4.5% |
|
Conductivity | 10%(w/v) water solution ≤200µS/cm |
70 |
| Propylene oxide | ≤1ppm | ＜0.18ppm |
| Propylene glycol | ≤2.5％ | 0.05% |
| Sum of Other Impurities | ≤1％ | 0.51% |
| Betadex | ≤1.5% | 0.39% |
| Residue on Ignition | ≤0.2％ | 0.09% |
| Heavy Metal | ≤20ppm | ＜10ppm |
| chloride | ≤0.05% | ＜0.05% |
| Bacterial endotoxins | ≤25EU/g | <20EU/g |
| TAMC(cfu/g) | ≤1000 | 80 |
| TYMC(cfu/g) | ≤100 | 30 |
| Salmonella/E. Coli (cfu/g) | Absent | Absent |
Storage: at room temperature, in tightly closed container.
Applications:
Hydroxypropyl-β-cyclodextrin (HP-β-CD) is one of the most widely used cyclodextrin derivatives in current scientific researches and industry applications. It mainly used in food, pharmaceutical and cosmetics industries.