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Name: Sulfobutyl ether-beta-cyclodextrin sodium salt
Other name : Betadex sulfobutyl ether sodium;
Sulfobutyl ether-β-cyclodextrin sodium salt;
Sulfobutyl Ether-Beta-cyclodextrin
CAS#: 182410-00-0
DMF NO.: 030167
Abbreviation: SBEBCD/SBE-β-CD
Molecular formula : C42H70-nO35 (C4H8O3S Na)n
Molecular weight: 1135+158n
Qaulity: injection grade
Standard: USP
Package:500g/bag , 1kg/bag , 2kg/bag, 10kg/drum , 20kg/drum
Use:medical
Features and applications:
Betadex sulfobutyl ether sodium(SBE-β-CD)is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate. Betadex sulfobutyl ether sodium(SBE-β-CD)has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.
Betadex sulfobutyl ether sodium mainly used in anti-cancer drugs, sucha as : Voriconazole/Posaconazole/Delafloxacin